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U.S. Department of State

Diplomacy in Action

Our Offices


The Bureau of International Security and Nonproliferation is organized into 12 offices:

Office of the Biological Policy Staff (BPS): BPS works to impede and roll back the threat of acquisition or use of biological weapons by state and non-state actors by overseeing U.S. implementation of the Biological Weapons convention, coordinating State Department efforts in support of the national strategy for countering biological threats, developing and promoting measures to prevent misuse of advances in the life sciences, and developing policies to use nonproliferation tools to impede and prevent bioterrorism.

Office of Conventional Arms Threat Reduction (CATR): CATR leads the working-level U.S. Government efforts to curb the proliferation of advanced conventional weapons such as man-portable air defense systems, major weapons systems and heavy military equipment (tanks, aircraft, missiles), sensors and lasers, and precision-guided munitions.

Office of Cooperative Threat Reduction (CTR): CTR oversees the diplomatic aspects of programs aimed at reducing the threat posed by terrorist organizations or states of concern seeking to acquire weapons of mass destruction expertise, materials and equipment. In addition to continued efforts in Iraq, the former Soviet Union, and Libya to engage former WMD experts, the global threat reduction programs are working to reduce the rapidly growing worldwide WMD threat posed by terrorists, non-state actors, and proliferant states.

Office of Counterproliferation Initiatives (CPI): CPI takes the lead in developing, implementing, and improving counterproliferation efforts, such as the proliferation security initiative or other efforts to interdict or deny shipments of WMD, and their means of delivery, and promoting observance of UN Security Council Resolution 1540.

Office of Export Control Cooperation (ECC): ECC formulates, coordinates, and strengthens U.S. nonproliferation export control assistance, including promotion of bilateral and multilateral coordination of assistance. ECC also manages the export control and related border security program to help governments establish, strengthen, and enforce export/border control systems and responsible export control policies consistent with international norms.

Office of Missile, Biological and Chemical Nonproliferation (MBC): MBC manages U.S. Government efforts to impede, roll back, and eliminate the proliferation of chemical and biological weapons, missile delivery systems for WMD (nuclear and CBW), and related equipment, materials, and technology.

Office of Multilateral Nuclear and Security Affairs (MNSA): MNSA has the lead role on a variety of multilateral nuclear nonproliferation, security, and disarmament issues, including: the Treaty on the Non-Proliferation of Nuclear Weapons; extra budgetary and policy support for safeguards, nuclear security, technical cooperation, and other programs under the International Atomic Energy Agency; U.S. bilateral safeguards and diplomatic efforts directed at encouraging states to conclude and implement comprehensive safeguards agreements and additional protocols; nuclear-weapon-free-zone treaties and protocols; security assurances; and G8 and EU nonproliferation and disarmament dialogues. The office leads in the development and formulation of U.S. Government policy through the chairmanship of the interagency Subcommittee on International Safeguards and Monitoring. MNSA also plays a supporting role for nonproliferation-related issues such as the safeguards aspects of fissile material cutoff.

Office of the Nonproliferation and Disarmament Fund (NDF): NDF develops, coordinates, executes, implements, and evaluates projects in coordination with State Department policymakers and the U.S. Government nonproliferation community to promote effective bilateral and multilateral nonproliferation and disarmament programs.

Office of Nuclear Energy, Safety and Security (NESS): NESS has the lead in developing U.S. policy related to peaceful nuclear cooperation policy, nuclear safety, nuclear export controls, and the physical protection of nuclear materials and facilities, in furtherance of U.S. nuclear nonproliferation goals.

Office of Regional Affairs (RA): RA supports the Bureau’s work on diplomatic responses to specific bilateral and regional WMD proliferation challenges, including today’s threats posed by Iran, North Korea, and Syria. It also will develop and support strategic dialogues with India, Pakistan, China, and other key states or groups of states for which the lead role is not assigned elsewhere within ISN.

Office of Strategic Communications and Outreach (SCO): SCO is the public affairs and press office for ISN. SCO also manages ISN’s legislative affairs and engages in outreach efforts for ISN issue areas with appropriate experts in academia, the private sector, and the NGO community.

Office of WMD Terrorism (WMDT): WMDT reduces the threat of WMD terrorism by establishing, strengthening, and maintaining the capabilities of international partners to deter, detect, defeat, and respond to terrorist attempts to use chemical, biological, radiological or nuclear materials.


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