Bureau of International Security and Nonproliferation
Our Mission
Preventing the spread of WMD, delivery systems, and advanced conventional weapons capabilities — and rolling back such proliferation where it has already taken root — is the mission of the Bureau of International Security and Nonproliferation (ISN). In close collaboration with other bureaus within the State Department, other U.S. agencies, and a diverse range of international and non-governmental partners, ISN tracks, develops, and implements effective responses to proliferation threats and shapes the international security environment to prevent their recurrence.
The Imposition of New U.S. Sanctions in Connection With a Key Iranian Nuclear Organization as Iran Refuses To Answer Questions Related to its Secret Nuclear Archive
Learn More The Imposition of New U.S. Sanctions in Connection With a Key Iranian Nuclear Organization as Iran Refuses To Answer Questions Related to its Secret Nuclear ArchiveThe Latest
Statement by the United States in General Debate
"We must recall our predecessors’ accomplishments in building a nonproliferation regime that has provided great benefits to all Parties and become a cornerstone of international peace and security. We must reaffirm our shared commitment to the NPT and the broader nonproliferation regime. And we must rededicate ourselves to preserving and strengthening them for future generations."
Full TextOffices
- Office of Conventional Arms Threat Reduction
- Office of Cooperative Threat Reduction
- Office of Counterproliferation Initiatives
- Office of Export Control Cooperation
- Office of Missile, Biological, and Chemical Nonproliferation
- Office of Multilateral Nuclear and Security Affairs
- Office of Nuclear Energy, Safety, and Security
- Office of Regional Affairs
- Office of Strategic Communications and Outreach
- Office of the Biological Policy Staff
- Office of the Nonproliferation and Disarmament Fund
- Office of Weapons of Mass Destruction Terrorism