An official website of the United States Government Here's how you know

Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Global network security and data protection concept, a grid of cells with a lock symbol in some of them around the Earth globe on deep blue space background, 3d illustration - Illustration

Bureau of International Security and Nonproliferation

Subscribe

Our Mission

Preventing the spread of WMD, delivery systems, and advanced conventional weapons capabilities — and rolling back such proliferation where it has already taken root — is the mission of the Bureau of International Security and Nonproliferation (ISN). In close collaboration with other bureaus within the State Department, other U.S. agencies, and a diverse range of international and non-governmental partners, ISN tracks, develops, and implements effective responses to proliferation threats and shapes the international security environment to prevent their recurrence.

Key Topics

Biological Weapons Convention

The United States is a Depositary Government for the Biological Weapons and Toxin Convention (BWC), which bans the development, production and stockpiling of an entire category of weapons of mass destruction. States Parties work to strengthen the Convention at annual Meeting of Experts and Meetings of States Parties, as well as review conferences taking place every five years. These meetings address all aspects of the Convention, including international cooperation and assistance in areas like disease surveillance capacity-building; developments in science and technology and the responsible conduct of the life sciences; national implementation of the Convention in laws and regulations; preparedness and response to suspicious outbreaks of infectious disease; and the institutional strengthening of the BWC.

Read More Biological Weapons Convention

Nonproliferation Sanctions

The United States imposes sanctions under various legal authorities against foreign individuals, private entities, and governments that engage in proliferation activities, including Iran, Syria, and North Korea.

Read More Nonproliferation Sanctions

Biological Weapons Convention

The United States is a Depositary Government for the Biological Weapons and Toxin Convention (BWC), which bans the development, production and stockpiling of an entire category of weapons of mass destruction.

Read More Biological Weapons Convention

CAATSA

Section 231 of the Countering America’s Adversaries Through Sanctions Act (“CAATSA,” or “the Act”) (Pub. L. 115-44,) was enacted on August 2, 2017. The President delegated to the Secretary of State, in consultation with the Secretary of the Treasury, the authority to implement Section 231 on September 29, 2017.

Read More CAATSA

The International Atomic Energy Agency

The International Atomic Energy Agency (IAEA) advances critical U.S. interests related to preventing the proliferation of nuclear weapons, strengthening global nuclear safety and security, and promoting the peaceful applications of nuclear energy, science, and technology.

Read More The International Atomic Energy Agency

U.S. Department of State

The Lessons of 1989: Freedom and Our Future