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The United States President’s Emergency Plan for AIDS Relief


Our Mission

The Office of the U.S. Global AIDS Coordinator and Global Health Diplomacy leads, manages, and oversees the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR). Through PEPFAR, the U.S. government has invested over $100 billion in the global HIV/AIDS response, the largest commitment by any nation to address a single disease in history, saving 25 million lives, preventing millions of HIV infections, and accelerating progress toward controlling the global HIV/AIDS pandemic in more than 50 countries.

World Aids Day 2023, Ambassador Dr. John Nkengasong

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Our Priorities


PEPFAR saves lives, prevents HIV infections, and accelerates progress toward achieving HIV/AIDS pandemic control in more than 50 countries around the world.

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PEPFAR ensures every dollar is optimally focused for impact through data-driven policies, and supports partner countries to do the same.

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PEPFAR reaches the populations that are most affected by the HIV/AIDS epidemic with innovative solutions that meet their needs.

Learn More About PEPFAR's Impact on Different Populations Populations


PEPFAR leverages the power of partnerships across multiple sectors to increase our impact and advance sustainability.

Learn More About PEPFAR's Partnerships Partnerships

U.S. Department of State

The Lessons of 1989: Freedom and Our Future