PEPFAR Home PEPFAR Home About Us Our Priorities Where We Work Results and Impact PEPFAR Partnerships Remarks and Releases Reports and Guidance HomeBureaus & OfficesThe United States President’s Emergency Plan for AIDS Relief...PEPFAR Home hide The United States President’s Emergency Plan for AIDS Relief Our Mission The Bureau of Global Health Security and Diplomacy leads, manages, and oversees the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR). Through PEPFAR, the U.S. government has invested over $110 billion in the global HIV/AIDS response, the largest commitment by any nation to address a single disease in history – saving 26 million lives, preventing millions of HIV infections, and accelerating progress toward controlling the global HIV/AIDS pandemic in more than 50 countries. Follow Us: Facebook Twitter Instagram YouTube Flickr The Latest September 4, 2025 PEPFAR’s Support of American Innovation to Reach up to 2 Million People by 2028 with Breakthrough HIV Drug Lenacapavir Today, the U.S. Department of State announced a market-shaping initiative by the President’s Emergency Plan for AIDS Relief (PEPFAR) to bring U.S.-based Gilead Sciences’ breakthrough drug lenacapavir to market in high-burden HIV countries. The initiative – which will promote global scale in production and distribution of the medication and catalyze further global investment – has […] September 4, 2025 Department of State, Gilead Sciences, and The Global Fund Announcement of Lifesaving and Innovative PEPFAR Initiative September 4, 2025 PEPFAR Commits to Distributing Breakthrough HIV Drug Lenacapavir Demonstrating American Excellence in Science and American Leadership in HIV Prevention December 1, 2024 PEPFAR World AIDS Day 2024 See All Our Priorities Progress Policies Populations Partnerships Progress PEPFAR saves lives, prevents HIV infections, and accelerates progress toward achieving HIV/AIDS pandemic control in more than 50 countries around the world. Learn More About PEPFAR's Progress Progress Policies PEPFAR ensures every dollar is optimally focused for impact through data-driven policies, and supports partner countries to do the same. Learn More About PEPFAR's Policies Policies Populations PEPFAR reaches the populations that are most affected by the HIV/AIDS epidemic with innovative solutions that meet their needs. Learn More About PEPFAR's Impact on Different Populations Populations Partnerships PEPFAR leverages the power of partnerships across multiple sectors to increase our impact and advance sustainability. Learn More About PEPFAR's Partnerships Partnerships
